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If overstimulation persists even at 300 mcg Semax, the issue is likely acetylcholinesterase inhibition sensitivitysome individuals require lower doses (150200 mcg) to avoid excessive acetylcholine accumulation

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Symptoms may include: Penile curvature or bending during erection Palpable hardened plaque or nodules Penile pain (especially in early or active phases) Erectile dysfunction Loss of length or girth While some cases stabilize on their own, many men seek treatment when symptoms persist or worsen

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Persistent lumps suggest the same area is being used too often