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These findings reveal a brain-gut circuit underlying opioid-induced constipation and suggest potential therapeutic strategies to mitigate this debilitating side effect

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Virtual Screening, ADMET Prediction, Molecular Docking, and Dynamic Simulation Studies of Natural Products as BACE1 Inhibitors for the Management of Alzheimer's Disease. Scientific Reports 14: 26431

Glutathione depletion has been documented in several neurodegenerative conditions

1E lower panel and Supplementary Fig